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Old 05-14-2010
khushboo khushboo is offline
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Default Permissive action of cortisol

Quote:
Originally Posted by omarnajat View Post
why not pancreas as it releases glucagon which function is to increase blood glucose

Glucagon alone can not stimulate production of PEPCK(phosphoenolpyruvate carboxykinase) rate limiting enzyme in Gluconeogenesis,rather it requires permissive action of cortisole for doing so....on the other hand cortisol and grothhormone can stimulate gluconeogenesis by their own...
so if we remove source of glucagon ; GH & Cortisol r still their to carry out gluconeogenesis..
but if we remove ant pituitary...glucagon is helpless...it can not produce PEPCK by it own....
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