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  1. USMLE Step 1 Forum
    a 44 year old female is found delirius late at night in the streets brought in by a young man who was kind enough to give her something sweet on the way to the hospital. BP is 130/80 pulse is 78 bpm. On examination she has nystagmus, she's ataxic and has limited eye movement. She then behaved...
  2. USMLE Step 1 Bits & Pieces
    What does insulin do to potassium and what does potassium do to insulin secretion is a concept that is frequently tested in USMLE Step 1. Let's summarize here and I'd be happy if you enrich this thread with your valuable posts. Insulin causes Potassium to shift into the cells thereby...
  3. USMLE Step 1 Mnemonics
    We all know Mudpiles which is a mnemonic for increased anion gap acidosis and it specifically stands for Methanol, Uremia, DKA, Phenformin/Paraldyhide, Iron/INH/Inborn error of metabolism, Lactic acidosis, Salicylates. Now how about the normal anion gap acidosis! In fact in USMLE they are more...
  4. USMLE Step 1 Mnemonics
    A-I Activates Lacat B-100-Binds to LDL receptor mediates VLDL secretion C-II -cofactor for lipoprotein lipase. b-48- mediates chylomicrone secretion. E- mediates Extra - remnant- uptake Hopefully will help memory process
  5. USMLE Step 1 Mnemonics
    USMLE Step 1 questions frequently ask about these very high yield three enzymes. They are called ABC enzymes as they all need ATP Biotin Carbon Dioxide These three enzymes are all carboxylases: Pyruvate Carboxylase Propionyl Co-A Carboxylase Acetyl Co-A Carboxylase
  6. USMLE Step 1 Forum
    I have been facing some questions that confused me and could not tell the difference between Myophosphorylase deficiency (McArdle) and the other one, Muscle Carnitine deficiency. Please anybody can simplify the distinction, any quick tip for the exam? Thanking you,
  7. USMLE Step 1 Mnemonics
    There's no better than the popular mnemonic Citrate Is Krebs Starting Substrate For Making Oxaloacetate Citrate Isocitrate Alfa Ketoglutarate Succinyl Co A Succinate Fumarate Malate Oxaloacetate
  8. USMLE Step 1 Forum
    Can anybody tell me what is the sequence of events like which is first glycogen or oxidative pathway I see several questions about this and I don't have a good reference
  9. USMLE Step 1 Recommended Threads
    Post and Poll Options were last updated on November 26th, 2013. In this poll we vote for the Best Biochemistry review book specific for the USMLE Step 1 Exam. Choice of Books Listed in the Poll You will notice that larger textbooks of biochemistry are not listed here, we are voting for...
  10. USMLE Step 1 Forum
    What is the name of these spots and what Vitamin deficiency causes it Courtesy of www.opt.indiana.edu
  11. USMLE Step 1 Classic Clues
    If the question stem describes a child with signs of chronic liver disease such as bleeding tendency, signs of liver cirrhosis, jaundice, elevated LFTs, ...etc. Plus a noticeable change in behavior such as clumsiness or even some Parkinsonian symptoms. Think Wilson's Disease immediately. They...
  12. USMLE Step 1 Forum
    Hey, How to tell them apart? They both common in Ashkenazi Jews They both cause Cherry red spot They both cause blindness They both kill early in life They both cause mental retardation They both cause seizures They both are autosomal recessive They both are lysosomal storage disorders...
  13. USMLE Step 1 Forum
    If the problem in hartnup disease is defective absorption of amino acids then how come we have access of them in the urine?
  14. USMLE Step 1 Bits & Pieces
    In response to a member's request in this thread http://www.usmle-forums.com/usmle-step-1-mnemonics/386-heme-synthesis-pathway-mnemonic.html We made this diagram available Have a look here click image to enlarge
  15. USMLE Step 1 Mnemonics
    Here's a mnemonic to remind us of the heme synthesis steps Ala placed in urine cup produces heme Aminolevulinic Acid --> Porphobilinogen --> Uroporphyrinogen --> Coproporphyrinogen --> Protoporphyrin (Protoheme) ---> Heme There are other intermediates in the long pathway but these are...
  16. USMLE Step 1 Bits & Pieces
    For the purposes of USMLE there are only two enzymes that require B12 as co-factor, these are: The conversion of homocysteine into methionine via the enzyme homocysteine methyl transferase which uses N5 methyl THF as another substrate converting it to THF. Therefore, deficiency of vitamin B12...
  17. USMLE Step 1 Forum
    Is it Cysteine or Cystine problem! I have to confusing references about it Please help
  18. USMLE Step 1 Mnemonics
    If you are like me having difficulty memorizing the sequence then this might help 1 Q Before Complex Attacking Fires 1 = Complex I (NADH Dehydrogenase) Q = Coenzyme Q (Complex II, Succinate Dehydrogenase feeding into it) B = Cytochrome b/c1 (Complex III) C = Cytochrome C A = Cytochrome a/a3...
  19. USMLE Step 1 Classic Clues
    Exclusively Breast Fed Baby + Born overseas or born at home Think Vitamin K deficiency as no injection was given and the breast milk is deficient in Vitamin K
  20. USMLE Step 1 Forum
    Can anybody tell me how do we get 32 ATPs from each glucose molecule I can't understand the calculation and also there's two questions about it in USMLE Consult
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