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  1. USMLE Step 1 Forum
    Hello, could someone kindly explain how does K+ levels in plasma affect Aldosterone secretion by the Glomerulosa? Thank you :notsure:
  2. USMLE Step 1 Forum
    Q1) What happens to Aldosterone levels in a Cushing's patient? Will they go down because of the negative feedback inhibition from the weak mineralocorticoids? Q2) What is the cause of polyuria in a Cushing's Patient? Is it because of osmotic diuresis from Hyperglycemia? In cushings as there is...
  3. USMLE Step 1 Forum
    29-yr-old female comes because of hot flashes, irritability, amenorrhea. Which of the following findings are likely to be seen 1) elevated androgen 2) elevated estradiol 3) reduced FSH 4) reduced inhibin plz explain also
  4. USMLE Step 1 Forum
    I am confused with “Rapidly induced TSH effects” Vs “Slowly induced TSH effects”. Are these effects pathological OR are the normal part of physiological mechanism. It’s mentioned in book that effects of rapidly induced TSH are iodide trapping, thyroglobulin synthesis, secretion of T4 in blood...
  5. USMLE Step 1 Forum
    IF PIF inhibits prolactin and somatostatin inhibits GH, how is it possible that when pituitary stalk is cut, only prolactin increases , why not GH also increases?
  6. USMLE Step 1 Forum
    Why do we get hypertension with this deficiency? Happy-2 Plus wouldn't RAAS be suppressed overtime so it wouldn't be due to Ang 2?
  7. USMLE Step 1 Forum
    Hey guys I was wondering how are the diamonds, square, and triangles are suppose to help you understand or remember Multiple Endocrine Neoplasia in FA 2013. Sorry if this a retarded question. :eek::D
  8. USMLE Step 1 Forum
    In uworld it is written that prednisolone chronic treatment decrease CRH, ACTH and also cortisol. BUT why cortisol is decresing it should be increase as we are giving exogenous cortisol(i.e prednisolone)
  9. USMLE Step 1 Forum
    Can someone explain what is the relationship between Progestrone and LH ??:confused::confused:
  10. USMLE Step 1 Forum
    Is prolactin regulated by circadian rhythm (as in FA) or by sleep cycle (as in kaplan Qbank) or its the same??? :confused::confused:
  11. USMLE Step 1 Forum
    Besides LH at pituitary and GnRH at hypothalamus Does testosterone have negative feedback on FSH also?
  12. USMLE Step 1 Forum
    why there is hypOnatremia and hypErkalemia?? adrenal crisis is decrease cortisol so how it also act as conn disease..
  13. USMLE Step 1 Forum
    glucagon causes hyperglycemia hyperglycemia inhibits GH so how does glucagon stimulate GH (as it's written in my book) ? thanks
  14. USMLE Step 1 Forum
    Why there is resetting of osmostat downward in pregnancy, menstrual cycle and volume depletion?
  15. USMLE Step 1 Forum
    It is actually GnRH analog BUT why it is used for precocious puberty. UW said its continuous infusion supress GnRH.
  16. USMLE Step 1 Forum
    What is the MAIN source of Estrogen Androgens In Premenopausal and Postmenopausal Women Males
  17. USMLE Step 1 Forum
    am kind of confused after i heard from Goljan audio that it is I 131 uptake which helps for the diagnosis of thyroid disorders. but i have already read on goljan pathology book that it the I 123 uptake which we need for the laboratory diagnosis. help me out. which is the one we should use???
  18. USMLE Step 1 Forum
    Why hypercalcemia produce diastolic hypertension ??
  19. USMLE Step 1 Forum
    why normal PTH in hypoalbuminemia? I think PTH should be decreased because low albumin levels attach less calcium so more free calcium is present which should decrease PTH. SOURCE:goljan 3rd ed. pg 493(diagram 22-15)
  20. USMLE Step 1 Forum
    How it is possible? PTH increases excretion of phosphate and in renal osteodystrophy PTH is increased.. Source: Goljan 3rd edition. Pg 411. (lab finding of renal osteodystrophy)