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  1. USMLE Step 1 Forum
    TH1 cells fail to produce IFN-GAMMA so decrease nutrophyll chemotactic this relation explains increase IgE???
  2. USMLE Step 1 Forum
    I have studied immunology from Levinson and I found it really easy. But now when i read it from Kaplan its too lengthy. And I personally think no ones gonna ask us such small details. is that so? Please help me out. The questions also I cant solve them too deep. Should I be using some other book?
  3. USMLE Step 1 Forum
    Is there a good viral defense mechanism in the MHC class 2 deficiency? getting confused.............:o:mad::toosad:
  4. USMLE Step 1 Forum
    Just want to confirm something.. is the mutation of CRCX4 will give you a FULMINANT HIV Course? i suppose cause directly will get to Th4 and no macrophage, CTL or NK help from them...? please enlighten me! a friend of mine got this question about mutation on CRCX4 :confused:
  5. USMLE Step 1 Forum
    What's the mechanism behind the development of sacroilitis, ankylosing spondylitis etc in Crohn's disease? Is it a hypersensitivity reaction? due to antibody/immune complex mediated damage of the joint? Is p-ANCA or any other antibody responsible for all these extraintestinal manifestations...
  6. USMLE Step 1 Forum
    CMV prion disease was associated with corneal transplant? please add to list or post a link to transplant associated infections in this thread? Thanks
  7. USMLE Step 2 CK Forum
    Breastfeeding The advantages of breastfeeding: • Passive transfer of T-cell immunity: Decreased risk of allergies and gastro* intestinal and respiratory infections (MTB3-p.339/KLN Pediatrics-p36) is it the IgA or is it the Tcell immunity playing a role ?
  8. USMLE Step 1 Forum
    can someone please advice me , how to improve the subject above , i did a stimulated test , and i scored badly for the above two subject , i have used kaplan , dit , but still ..... please advice , thanks .
  9. USMLE Step 1 Forum
    Ok, this one is probably a very overlooked topic but a very High Yield one, so lets start a discussion and postings of useful links and Vids explaining USMLE Lab Techniques found in Genetics/Immuno/Biochem etc. ( PCR, Blots, Assays, Coombs for instance) Kindly post useful videos that you have...
  10. USMLE Step 1 Forum
    Hi Guys, I am stuck with a problem.. :( can somebody please explain the exact mechanism of GVHD? What type of cells does it involve? and why there's no GVHD in Bare Lymphocyte Syndrome? Thanks
  11. USMLE Step 1 Forum
    Dear Friends, I have completed my first read with kaplan LN for all the subjects except for pathology..i am planning to start FA with UW, my exam date on December..should i read kaplan LN for Biochemistry and for immunology, or shall i stick with FA with UW for all the subjects because when i...
  12. USMLE Step 1 Forum
    Hi guys, please i would like some advice about how do i have to study Complement in Immuno, Kaplan emphasizes on the functions and the differences between them but ive heard people talking about studying complement with najeeb lectures which gives complement very detailed, so the question is...
  13. USMLE Step 1 Forum
    Hey guys, why is c3 level low in certain diseases, such as rheumatoid arthritis, type III hypersensitivity? can any of you tell me all the possible diseases and the mechanisms of decreased C3? really appreciate it! :sorry:
  14. USMLE Step 1 Forum
    Can someone explain if conjugated vaccines (like HiB) activate T cells? I thought that the whole point of conjugation is to induce T cells, which can allow class switching and generate long term antibodies. If the vaccine is only activating B cells, we would only get IgM, which doesn't last...
  15. USMLE Step 1 Forum
    1. brutons is B cell defect (proB cell >>>\>>> preB cell), then why there is absent thymic shadow ? as mentioned in first aid ???? 2012 edition 2. why PCP pneumonia infection is more common in HIM (hyper IgM has problem with B cell class switching, so bacterial infection not viral infection...
  16. USMLE Step 1 Forum
    killed vaccine generate humoral immunity. does it involve class switching? if yes then why do we require booster as memory has already been generated! que 2- tab( typhoid) vaccine is killed or live attenuated? que 3- conjugated pnummococcal , flu , menningococcal are killed or live?
  17. USMLE Step 1 Forum
    am now reading on the complement system[pathology part]. and i got some difficulty of understanding it. is the complement system always helpful or it has something harm to our body in addition???
  18. USMLE Step 1 Forum
    Why does eosinophilia occur in atypical pneumonia secondary to C. Trachomatis? Hey guys, this is my first post here so I don't know the proper etiquette for asking questions - just let me know if there's any more information I should include in the future. Can anyone explain this to me (this is...
  19. USMLE Step 1 Forum
    Which pathway is activated by immune-complexes - Alternative or classical pathway? Can anyone make it easy, I don't understand this concept?
  20. USMLE Step 1 Forum
    Why dont these patients develope graft vs host disease? They dont have MHC II > no CD4 cells and also weak CD8 function.. In Graft vs host the graft attacks the patuent.. What's thr decrease in CD 4 has to do with the grafts ability to attack the recipient?