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  1. USMLE Step 2 CK Forum
    I always find these Fungus questions - Blastomycosis , Coccidiidomycosis, Histoplasmosis questons very difficult. I dont know whats the trick with all the overlapping clinical features and Geographic distribution. A few points i remember so far Blastomycosis- missisipi, ohio , highest...
  2. USMLE Step 1 Forum
    from kaplan, m confused, what is D and E here? nuclear membrane ? and btw, rest of labelling correct ???
  3. USMLE Step 1 Forum
    A 32-year-old woman who is seropositive for HIV is admitted to the hospital because of increasing confusion. She dies 2 days later. A tissue section of the meninges obtained at autopsy is shown. Which of the following is the most likely causal organism? A. Candida albicans B. Cryptococcus...
  4. USMLE Step 1 Forum
    A 68 year old woman is admitted to hospital for evaluation of gross hematuria. 2 days after admission she develops aphasia & right hemiplegia, followed shortly by coma & death. The cut surface of one of her kidneys as seen at autopsy is shown. Which of the following was the most likely cause of...
  5. USMLE Step 1 Forum
    She came in with complains of difficult swallowing, fatigue, abdominal discomfort, weight loss, and pale skin seen during PE. Biopsy was done, and in histochemical staining cells was positive for CD 117, vimentin , and CD 34. Whats the MOST possible origin of these cells? a. epithelial...
  6. USMLE Step 1 Bits & Pieces
    I noticed that a lot of us are having difficulties interpreting X-rays/CTs, MRIs and histology slides so I figured a thread dedicated to high yield images might be helpful. Feel free to attach images and get everyone to participate in learning!
  7. USMLE Step 1 Forum
    38 year old woman has seizures,increased Intracranial pressure and weakness in legs. CNS tumor is suspected and after imaging studies biopsy is done. The biopsy shows whorled pattern of cells seen here: click image to enlarge which of the following will most likely be positive on...
  8. USMLE Step 1 Forum
    Polymyositis and dermatomyositis are linked to each other in many features...what is the following feature is present only in polymyositis in contrast to dermatomyositis..? a) gottron's papules b) heliotrope rash c) perimysial inflammation d) endomysial inflammation e) antibody mediated damage...
  9. USMLE Step 1 Forum
    A 39-year-old woman has noticed an enlarging mass in her left breast for the past 2 years. The physician palpates a 4- cm firm mass. A simple mastectomy is performed with axillary lymph node sampling and plastic reconstruction of the breast. On gross sectioning, the mass has a soft, tan, fleshy...
  10. USMLE Step 1 Forum
    A 55-year-old man has had nausea and vomiting for several months. He has experienced no hematemesis. On physical examination, there is no abdominal tenderness, and bowel sounds are present. Upper gastrointestinal endoscopy shows erythematous areas of mucosa with thickening of the rugal folds in...
  11. USMLE Step 1 Bits & Pieces
    Review of the Childhood Primary Brain Tumors: 1. Pilocytic ASTROCYTOMA ("Pilocytic" refers to hair-like, which often describes the presence of long processes such as Rosenthal fibers) A - composed of Astrocytes ("astrocytes are fabulous" so GFAP positive) S - slow-growing cysts, benign, good...
  12. USMLE Step 1 Bits & Pieces
    Hi guys. i would like to summarize IF of some Dermatologic Problems. I. SLE associated Skin Lesion: Click image to enlarge Aka Band Test of SLE.Deposites are located along the Basal Membrane. II. Pemphigus Vulgaris Click image to enlarge Note the stratum spinosum intercellular staining...
  13. USMLE Step 1 Bits & Pieces
    Here's a list of Nephrotic syndrome diseases with their corresponding histomorphologic images. Click image to enlarge MCD Click image to enlarge Note: There is no Space between Podocyte processes. Compare it with normal: Click image to enlarge This is From Jaquiera Histology. Focal...
  14. USMLE Step 1 Bits & Pieces
    Guys I'm doing all this nephritic and nephrotic syndrome in Goljan RR. And I think that looking at the histomorphology of them is the best way to memorize all the IC patterns and deposits. hope these will help. click image to enlarge Berger IgA GN: H&E: click image to enlarge IF...
  15. USMLE Step 1 Forum
    A 45-year-old man visits his personal physician for a persistent fever. On exam, he has lymphadenopathy. As part of a more extensive workup, a supraclavicular lymph node biopsy is taken. A microscopic image from the biopsy is shown in the figure. What is the patient's most likely diagnosis? A...
  16. USMLE Step 1 Forum
    Where is the action of alpha1 adrenergic dugs in this pic (Its from Kaplan Qbank "QID 1148") They say answer E and say that E is smooth muscle =\ I think this is wrong, as E is endothelium and the receptor is in D which is smth msl :SSS Any idea guys?? click image to enlarge
  17. USMLE Step 1 Forum
    Can anyone please give a site where normal histology of breast ducts are explained..i mean those carcinomas and paget's disease related histologies ..i want to know the normal histological features..really feeling confused about the histology of those disease without knowing normal...
  18. USMLE Step 1 Forum
    Q2: I think it is B. The time till onset of symptoms (18 hours) is way too long for it to be epidural. Subdural makes more sense, slow bleeding from veins. Q14: I know it's the pre-motor cortex but its so hard to tell which one it is on the internal view. Can you please tell me all the...
  19. USMLE Step 1 Forum
    The following figure shows a firm nodule with pigmented acanthosis in a 36-y-old woman. In histology, interwining bundles of collagen and fibroblasts are characteristic. What is the most likely diagnosis? A) Epidermal inclusion cyst B) Fibroepithelial polyp C) Dertmatofibroma D)...
  20. USMLE Step 1 Forum
    A 56-year-old African-American female presented with numerous pigmented papules in the creases of her neck, axilla, and inguinal region. Histologic sections of skin (figure below) show a polypoid lesion with overlying mildly acanthotic epidermis. It consists of a central connective tissue core...
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