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pharmacology-

  1. USMLE Step 1 Forum
    The plasma levels of Ketoconazole are lower than normal following its oral absorption in patients treated with Lansoprazole. What is the reason for this? A) The induction of enzymes that metabolize ketoconazole B) Ketoconazole requires an acid environment for its oral absorption C) Lansoprazole...
  2. USMLE Step 1 Forum
    Which statement below is accurate regarding aspirin overdose? A) N-acetylcysteine should be given immediately B) The metabolism rate of aspirin is first-order C) Elimination rate is directly proportional to plasma concentration D) Increasing urinary pH would be beneficial E) Plasma...
  3. USMLE Step 1 Forum
    Which of the following is least likely to have an adverse drug interaction with phenelzine? A) Levodopa B) Ropinirole C) Tolcapone D) Propofol E) Pseudoephedrine
  4. USMLE Step 1 Forum
    Which of the following is most suitable for migraine prophylaxis in an otherwise healthy 30-year-old woman? A) Ergotamine B) Paracetamol C) Propranolol D) Carbamazepine E) Sumatriptan
  5. USMLE Step 1 Mnemonics
    3 As of Buspirone A - partial Agonist A - 5 HT1 type A receptor A - Anxiety disorders ABCD of Sumatriptan A - Acute migraine treatment / Asthenia as a side effect B - Basoconstriction ("v") of cerebral vessels C - Coronary vasospasm D - 5 HT1 type D receptor "SETRON" SE - SEerotonin...
  6. USMLE Step 1 Forum
    An AIDS patient who is being treated with multiple drugs, including AZT, lamivudine, indinavir, ketoconazole, and cotrimoxazole, develops breast hypertrophy, central adiposity, hyperlipidemia, insulin resistance, and nephrolithiasis. If this changes are related to his drug treatment, which of...
  7. USMLE Step 1 Forum
    Gentamicin would be an ineffective drug for which of the following organisms? A) E. coli B) B. fragilis C) Pseudomonas D) Listeria if combined with ampicilin E) Proteus
  8. USMLE Step 1 Forum
    guys i dont understand How does propranolol act in migraine headache? :redcheeks; plz help:toosad:
  9. USMLE Step 1 Forum
    A thirty-five-year-old male, formerly a heroin abuser, has been on methadone maintenance for the last thirteen months. Two weeks ago, he had a positive tuberculosis skin test (PPD test), and a chest radiograph showed evidence of right upper lobe infection. He was started on standard...
  10. USMLE Step 2 CK Forum
    IN UW they said that OCPs not associated with weight gain is that correct ?? they said that older OCPs only may cause insulin resistance but now lower dose formulation carry no risk .
  11. USMLE Step 1 Forum
    A- Bendroflumethiazide B- Inhaled insulin C- Glucagon D- Insulin glargine E- Acarbose F- Gliclazide G- Pioglitazone H- Orlistat I- Insulin lispro J- Metformin Link each of 1 to 5 below with the most appropriate item from A to J: 1- Lactic acidosis 2- Rapid hypoglycaemic effect 3-...
  12. USMLE Step 1 Forum
    Which of the following antibacterials is most suitable for treatment of a lower urinary tract infection in a 28-year-old woman who is 10 weeks pregnant? A) Amoxicillin B) Trimethoprim C) Tetracycline D) Erythromycin E) Flucloxacillin
  13. USMLE Step 1 Forum
    in an experimental lab what would u expect the effect of alpha-agonist on A-V PO2 difference a)increase b)decrease c)no change
  14. USMLE Step 1 Mnemonics
    This is quite long...but it may help M - Misreading of code N - Neuromuscular block O - Ototoxicity / O2 dependent uptake P - Porin channels need it / "P" site Q - Quiet the bacteria down (bactericidal) R - Renal toxicity S - Synergistic with beta lactam T - Thirty S (30S) ribosomal subunit /...
  15. USMLE Step 1 Forum
    A 26 year old female with a history of asthma and grave's disease comes to the emergency room with diaphoresis, hypertension, anxiety, tachycardia, and palpitations. The attending physician would like to give her a beta-blocker. Which beta-blocker do you recommend? A - Timolol B - Propanolol C...
  16. USMLE Step 1 Mnemonics
    Bc - Bacteriostatic B - Binds 30S B - Borrelia burgdorferi & Brucella B - Buddy "rocky" (Rocky mountain spotted fever) B - Bones & teeth problems B - Bad for your skin (phototoxicity) B - Bening pseudotumor cerebri B - Bestibular problems (I know!...vestibular)
  17. USMLE Step 1 Forum
    A 60-year-old epileptic woman who has been on the same dose of phenytoin for 20 years develops cerebellar ataxia with nystagmus. Her other medication consists of folic acid, hormone replacement therapy (HRT) and furosemide prescribed for ankle swelling and mild hypertension. Routine...
  18. USMLE Step 1 Forum
    Individuals who are slow acetylators (i.e. have a relatively low activity of hepatic N-acetyltransferase): A) Have a prevalence of 15-20 per cent in European caucasians B) Are more likely to develop thrombocytopenia, nephrotic syndrome and rash during gold treatment C) Are more likely to...
  19. USMLE Step 1 Forum
    A 78 year old male currently receiving treatment for malignant lymphoma reports to the ER complaining of pain when urinating and hematuria. The patient hands a list of medications he is on to the ER physician. What is the most likely drug responsible for this man’s urinary symptoms? A -...
  20. USMLE Step 1 Forum
    Uworld says that according to case control studies, lithium is not found to be a significantly teratogenic..it can be used in pregnancy although lamotrigine is the alternative..However it is advisable to perform echocardiography to exclude any possible anomalies.. Here is the link...
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