The plasma levels of Ketoconazole are lower than normal following its oral absorption in patients treated with Lansoprazole. What is the reason for this?
A) The induction of enzymes that metabolize ketoconazole
B) Ketoconazole requires an acid environment for its oral absorption
Which statement below is accurate regarding aspirin overdose?
A) N-acetylcysteine should be given immediately
B) The metabolism rate of aspirin is first-order
C) Elimination rate is directly proportional to plasma concentration
D) Increasing urinary pH would be beneficial
3 As of Buspirone
A - partial Agonist
A - 5 HT1 type A receptor
A - Anxiety disorders
ABCD of Sumatriptan
A - Acute migraine treatment / Asthenia as a side effect
B - Basoconstriction ("v") of cerebral vessels
C - Coronary vasospasm
D - 5 HT1 type D receptor
SE - SEerotonin...
An AIDS patient who is being treated with multiple drugs, including AZT, lamivudine, indinavir, ketoconazole, and cotrimoxazole, develops breast hypertrophy, central adiposity, hyperlipidemia, insulin resistance, and nephrolithiasis. If this changes are related to his drug treatment, which of...
A thirty-five-year-old male, formerly a heroin abuser, has been on methadone maintenance for the last thirteen months. Two weeks ago, he had a positive tuberculosis skin test (PPD test), and a chest radiograph showed evidence of right upper lobe infection. He was started on standard...
B- Inhaled insulin
D- Insulin glargine
I- Insulin lispro
Link each of 1 to 5 below with the most appropriate item from A to J:
1- Lactic acidosis
2- Rapid hypoglycaemic effect
Which of the following antibacterials is most suitable for treatment of a lower urinary tract infection in a 28-year-old woman who is 10 weeks pregnant?
This is quite long...but it may help
M - Misreading of code
N - Neuromuscular block
O - Ototoxicity / O2 dependent uptake
P - Porin channels need it / "P" site
Q - Quiet the bacteria down (bactericidal)
R - Renal toxicity
S - Synergistic with beta lactam
T - Thirty S (30S) ribosomal subunit /...
A 26 year old female with a history of asthma and grave's disease comes to the emergency room with diaphoresis, hypertension, anxiety, tachycardia, and palpitations. The attending physician would like to give her a beta-blocker. Which beta-blocker do you recommend?
A - Timolol
B - Propanolol
Bc - Bacteriostatic
B - Binds 30S
B - Borrelia burgdorferi & Brucella
B - Buddy "rocky" (Rocky mountain spotted fever)
B - Bones & teeth problems
B - Bad for your skin (phototoxicity)
B - Bening pseudotumor cerebri
B - Bestibular problems (I know!...vestibular)
A 60-year-old epileptic woman who has been on the same dose of phenytoin for 20 years develops cerebellar ataxia with nystagmus. Her other medication consists of folic acid, hormone replacement therapy (HRT) and furosemide prescribed for ankle swelling and mild hypertension. Routine...
Individuals who are slow acetylators (i.e. have a relatively low activity of hepatic N-acetyltransferase):
A) Have a prevalence of 15-20 per cent in European caucasians
B) Are more likely to develop thrombocytopenia, nephrotic syndrome and rash during gold treatment
C) Are more likely to...
A 78 year old male currently receiving treatment for malignant lymphoma reports to the ER complaining of pain when urinating and hematuria. The patient hands a list of medications he is on to the ER physician. What is the most likely drug responsible for this man’s urinary symptoms?
Uworld says that according to case control studies, lithium is not found to be a significantly teratogenic..it can be used in pregnancy although lamotrigine is the alternative..However it is advisable to perform echocardiography to exclude any possible anomalies..
Here is the link...