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step-1-questions

  1. USMLE Step 1 Forum
    which of the following can give a positive benedicts test in high concentrations? a)sucrose b)trehalose c)cellulose d)chitin 5)aspirin
  2. USMLE Step 1 Forum
    TACGATCATAT is an oligonucleotide probe used to construct a cDNA library to study the transcriptome of genetically modified mice. Which of the following coding strands will correctly hybridize with the probe in question? A- TACGATCATAT B- ATATGATCGTA C- AUGCUAGUAUA D- GCATATACGCG E- AUAUGAUCGUA
  3. USMLE Step 1 Forum
    Physical examination of a young healthy man revealed positive accommodation reflex. The mechanism by which this reflex is executed is which of the following? A- Lens becomes less convex B- Sympathetic stimulation C- Contraction of the zonules of Zinn D- Increased tension in lens capsule E-...
  4. USMLE Step 1 Forum
    A 55 year old man who's working at a nuclear plant has accidentally been exposed to a vast amount of radiation. He runs to the ER extremely anxious and demands immediate care. Which of the following systems could first show symptoms? A- Cardiovascular B- Renal C- Respiratory D- Reproductive E-...
  5. USMLE Step 1 Forum
    The sequence of transcription, transportation, and translation is accomplished respectively by? A- mRNA, tRNA, and rRNA B- tRNA, mRNA, and rRNA C- rRNA, tRNA, and mRNA D- mRNA, rRNA, and tRNA E- tRNA, rRNA, and mRNA F- rRNA, mRNA, and tRNA
  6. USMLE Step 1 Forum
    A 45 woman was relieved when the told her that the subcutaneous lump biopsy report is positive for a benign lesion. Which of the following most likely have been reported? A- Infiltration into surrounding tissues B- Prominent mitotic figure C- Encapsulation D- Anaplasia E- Metastasis
  7. USMLE Step 1 Forum
    A 36 years HIV positive man presented with classical symptoms of pneumonia. Chest X ray showed bilateral consolidation. Organism cultured from the sputum was lysed by ethylhydocupreine (optochin). What is the most likely infecting agent? A- Streptococcus agalactiae B- Streptococcus pneumoniae...
  8. USMLE Step 1 Forum
    Protein synthesis a process by which the DNA encodes for the production of amino acids and proteins. During this process which of the following refers to the three unit nucleotides found on tRNA? A- Codon B- Ribozyme C- Base pair D- Anticodon E- Insertion sequence
  9. USMLE Step 1 Forum
    55 year old overweight man is told by his doctor to lose weight. He decides to undertake a rigorous exercise program. On his first day out, he has jogged for 15 minutes when he experiences the sudden onset of chest pain. Fortunately, the chest pain is relieved by rest. His doctor performs an...
  10. USMLE Step 1 Forum
    Which of the following receptors is innervated by the Vagus nerve? A- Carotid sinus receptors B- Central chemoreceptors C- Aortic arch receptors D- Pulmonary artery receptors E- Atrial receptors
  11. USMLE Step 1 Forum
    A heavy smoker was found to have a stratified squamous epithelium in his bronchi. This pathology can be attributed to which of the following? A- Physiologic hyperplasia B- Pathologic hyperplasia C- Metaplasia D- Dysplasia E- Hypertrophy
  12. USMLE Step 1 Forum
    A man presented with a clinical picture of recurrent headaches, lethargy, and blurred vision particularly after exercise or fasting. His blood glucose during one of the attacks measured 35 mg/dl. Concomitant insulin and C peptide levels were reportedly higher than normal values. Which of the...
  13. USMLE Step 1 Forum
    Prevalence of homozygotes in a population is 1%. If a woman is a known carrier marries somebody from that population then what is the probability that they'll produce an affected homozygous child? A- 0.09 B- 0.07 C- 0.05 D- 0.025 E- 0.25 F- 0.50 G- 0.10
  14. USMLE Step 1 Forum
    In the lab you have two groups of mice. You transfected group 1 with a gene that makes them produce more IL2. The other group 2 you did not transfect. Then you inoculated both groups with tumor cells. You noticed an enhanced immunity in group 1. This enhanced immunity can be explained by...
  15. USMLE Step 1 Forum
    A US soldier returned from Iraq with a skin lesion on his right upper arm. The lesion was papular then developed into a nodular 4X5 cm crusting with irregular sharp border. Giemsa stain of biopsy showed inclusions with histiocytes. Which is the most likely infecting organism? A- Leishmania...
  16. USMLE Step 1 Forum
    A 44 yo male who is suffering from lukemia developed a generalized body rash. The rash described as multiple erythematous patches. Some of the patches have central pale eroded areas. This condition could be due to which of the following? A- Ebstien bar virus B- Cytomegalovirus C- Human...
  17. USMLE Step 1 Forum
    Drug X has been shown to increase activity levels of receptor activator for nuclear factor Kappa B ligand (RANKL). Drug X is likely to be which of the following? A- Pamidronate B- Teriparatide C- Thyroxine D- Alendronate E- Estrogen
  18. USMLE Step 1 Forum
    a 34 year old female immigrant from eastern Europe presents to the outpatient clinic with chronic cough. She has lost 5 Kilograms in the past three months. She also complains of occasional mild hemoptysis. An intradermal injection is done, and after 2 days the site of injection becomes indurated...
  19. USMLE Step 1 Forum
    A 41 year old man with history of drug abuse presented with a skin lesion on his right leg. Histopathologic examination showed the slide below. What is the likely cause of this condition? A- Human herpesvirus 8 B- Human Immunodeficiency virus C- JC virus D- Human Papilloma virus E-...
  20. USMLE Step 1 Forum
    A 57 year old man has undergone hip replacement surgery. Before surgery all hematologic and clotting studies were normal. Surgery was complicated with excessive blood loss and he has been transfused 6 units of PRBCs. Postoperative he has done well and discharged home. Next day he accidentally...
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