[46418]

Why do we get hypertension with this deficiency? Happy-2

Plus wouldn't RAAS be suppressed overtime so it wouldn't be due to Ang 2?

 

[vero]

Check the diagram on FA2013 pag 291: you can see that with this deficiency mineralcorticoids will accumulate, while corticosteroids and sex hormons won't (the production of hormons on the right of the diagram is absent). Because of increased levels of aldosterone, you'll also have fluid retention with high BP and decreased levels of K+...
hope it helps

 

[46418]

Thanks vero!