 # 32 ATPs per glucose molecule?

17567 Views 7 Replies 6 Participants Last post by  frenkert
Can anybody tell me how do we get 32 ATPs from each glucose molecule
I can't understand the calculation and also there's two questions about it in USMLE Consult
• 1
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It can be 32 and it can be 30 depending on which shuttle

in the case of 32 here's the calculation:

Glycolysis 2 ATPs/glucose
if NADH enters through G3P shuttle it will yield 3 ATPs
so 2x3= 6 ATPs

Each glucose gives two pyruvates
Each pyruvate entering TCA will give off 12ATPs
so 12x2 = 24

24+6+2 = 32

am sure you'll understand how malate shuttle gives 30 ATPs instead
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• 5
Each glucose gives two pyruvates
I think level1 confusion stems from the fact that he forgot that each glucose gives two pyruvates

Always remember the glycolysis equation

Code:
``Glucose + 2Pi + 2ADP + 2NAD = 2 Pyruvate + 2ATP + 2NADH + 2H + 2H2O``
• 5
very good job ... but ....

It can be 32 and it can be 30 depending on which shuttle

in the case of 32 here's the calculation:

Glycolysis 2 ATPs/glucose
if NADH enters through G3P shuttle it will yield 3 ATPs
so 2x3= 6 ATPs

Each glucose gives two pyruvates
Each pyruvate entering TCA will give off 12ATPs
so 12x2 = 24

24+6+2 = 32

am sure you'll understand how malate shuttle gives 30 ATPs instead
thats very cool but i think .. u all may forgot a step to convert pyruvate to Acetyl coA .. which yealds an Another mol. of NADH which add 3 ATP per pyruvate so Add 6 ATP per Gulcose which mean 1 Mol. of Glucose yealds 38 ATP per Glucose not 32 ATP am i right ?! • 4
thats very cool but i think .. u all may forgot a step to convert pyruvate to Acetyl coA .. which yealds an Another mol. of NADH which add 3 ATP per pyruvate so Add 6 ATP per Gulcose which mean 1 Mol. of Glucose yealds 38 ATP per Glucose not 32 ATP am i right ?! You are absolutely right • 1
You are absolutely right Betro. Glycolysis can produce either 6 or 8 ATPs, so by the end of KREBS CYCLE (36 or 38) depending on wt ATP produced from glycolysis. It can be 32 and it can be 30 depending on which shuttle

in the case of 32 here's the calculation:

Glycolysis 2 ATPs/glucose
if NADH enters through G3P shuttle it will yield 3 ATPs
so 2x3= 6 ATPs

Each glucose gives two pyruvates
Each pyruvate entering TCA will give off 12ATPs
so 12x2 = 24