A 54-year-old man is admitted to the hospital with cough and dyspnea, which over a period of years has led to marked respiratory embarrassment and cyanosis. Chest x-ray film of the lungs shows bilateral lower lobe ground-glass infiltrates. Wedge biopsy of the lung demonstrates airspaces
filled with macrophages containing lipid, periodic acid-Schiff (PAS)-positive granules, and lamellar bodies. There is an accompanying interstitial pneumonitis, hyperplasia of the septal lining epithelial cells, and desquamation of epithelial cells into alveoli. The lamellar bodies
within the macrophages are composed of which of the following?
A. Amyloid
B. Calcitonin
C. Fibrin
D. Hemosiderin
E. Surfactant
Explanation:
Full explanation in first response.
filled with macrophages containing lipid, periodic acid-Schiff (PAS)-positive granules, and lamellar bodies. There is an accompanying interstitial pneumonitis, hyperplasia of the septal lining epithelial cells, and desquamation of epithelial cells into alveoli. The lamellar bodies
within the macrophages are composed of which of the following?
A. Amyloid
B. Calcitonin
C. Fibrin
D. Hemosiderin
E. Surfactant
Explanation:
Full explanation in first response.