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ACE inhibitors Nephrotoxic or Nephroprotective

21249 Views 17 Replies 11 Participants Last post by  soni1075
In Goljan it is given,

that ACE inhibitors are beneficial in diabetic nephropathy cause they maintain renal perfusion beyond efferent arteriole and thereby supplying blood to kidney parenchyma.

but in UW its given ACE mediated nephrotoxity is due to :


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sorry but can u plz stress on their mechanism???

i mean to say that how they cause hypoperfusion even if they are causing efferent arteriolar dilation???
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