ACE inhibitors Nephrotoxic or Nephroprotective

21249 Views 17 Replies 11 Participants Last post by soni1075, Dec 10, 2016

shaan.medico

Discussion Starter · Feb 9, 2011

In Goljan it is given,

that ACE inhibitors are beneficial in diabetic nephropathy cause they maintain renal perfusion beyond efferent arteriole and thereby supplying blood to kidney parenchyma.

but in UW its given ACE mediated nephrotoxity is due to :

"RENAL HYPOPERFUSION"

??????????????
:notsure::notsure::notsure::notsure:

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shaan.medico

Discussion Starter · #3 · Feb 9, 2011

sorry

sorry but can u plz stress on their mechanism???

i mean to say that how they cause hypoperfusion even if they are causing efferent arteriolar dilation???

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