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Ménétrier disease
Is a disease in which there's hypertrophy of the gastric mucosa causing huge rugae These cells produce huge amounts of mucin and thus they may cause protein losing enteropathy and they'll replace the parietal cells and so less HCl secretion therefore no ulcer risk.
However, the uncontrolled hypertrophy may transform to malignancy and therefore patients need to be frequently monitored.
The disease is usually self limited in children.
Is a disease in which there's hypertrophy of the gastric mucosa causing huge rugae These cells produce huge amounts of mucin and thus they may cause protein losing enteropathy and they'll replace the parietal cells and so less HCl secretion therefore no ulcer risk.
However, the uncontrolled hypertrophy may transform to malignancy and therefore patients need to be frequently monitored.
The disease is usually self limited in children.