USMLE Forums banner
1 - 11 of 11 Posts

·
Registered
Joined
·
209 Posts
Discussion Starter · #1 ·
A 68-year-old man has had malaise for over a year. On physical examination, there are no abnormal findings. His hemoglobin is 10.5 g/dL, Hct 31.5%, MCV 88 fL, platelet count 211,000/microliter, and WBC count 6980/microliter. His total serum iron is 130 microgm/dL total iron binding capacity (TIBC) 230 microgm/dL, and soluble serum transferrin receptor is normal. A bone marrow biopsy is performed and microscopic examination shows that maturation is occurring in all cell lines and there are no abnormal cells seen. Stainable iron in the bone marrow is increased. Which of the following underlying diseases is he most likely to have?

A Diverticulosis
B Hepatitis C infection
C Systemic lupus erythematosus
D Atrophic gastritis
E Fanconi anemia
 

·
Registered
Joined
·
487 Posts
hmm...ACD is asso with chronic inflammatory conditions mostly non infectious like autoimmunity related chronic inflammation e.g. rheumatoid arthritis...n also alcohol n malignancy...

its common in RA n in option given i felt only SLE is chronic inflammatory..

let c wt is correct ans... :eek:
 

·
Registered
Joined
·
919 Posts
hmm... hep c seems to be the only logical answer, in which the blood is affected to cause increased iron levels but not aplastic or megaloblastic anemia. n SLE doesnt seem right because he's been fatigued for a YEAR!!
 
1 - 11 of 11 Posts
This is an older thread, you may not receive a response, and could be reviving an old thread. Please consider creating a new thread.
Top