A pharmacologist discovered a new fungal metabolite with unusual antimicrobial properties. It naturally concentrates in the endosomes, lysosomes, and phagolysosomes of cells and directly kills microorganisms (e.g Mycobacterium tuberculosis) that are normally resistant to degradation in the phagolysosome. The metabolite has the undesirable effect of increasing the PH within phagolysosomes. Which of the following processes will be primarily affected?
A- Class I MHC molecule peptide loading
B- Class II MHC molecule peptide loading
C- Peptide binding to T lymphocyte receptor αβ
D- Peptide binding to T lymphocyte receptor γδ
A- Class I MHC molecule peptide loading
B- Class II MHC molecule peptide loading
C- Peptide binding to T lymphocyte receptor αβ
D- Peptide binding to T lymphocyte receptor γδ