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An elderly man comes to medical attention because of anemia and multiple infections. Physical examination is remarkable for hepatosplenomegaly. An automated blood count demonstrates pancytopenia. Review of the peripheral smear by a hematologist demonstrates rare, distinctive, neoplastic white cells covered by fine, hairlike projections. Which of the following characteristics would likely be associated with these cells?
A. Birbeck granules
B. Elevated leukocyte alkaline phosphatase
C. Philadelphia chromosome
D. Positive tartrate-resistant acid phosphatase
E. Production of Bence-Jones proteins
 
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