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Autonomy is the patient's right to accept or refuse any treatment - even life saving one - given that he/she was competent and well informed about risks and benefits. Autonomy takes precedence over anything else when it comes to USMLE questions (ALWAYS!) and real life practice (most of the time).

Beneficence is simply applying the best interest standard. its used when the patient is incompetent and the surrogate making the decision fails to use the subjective standard or substituted judgement criteria.
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