BPH Treatment?

khanar · Apr 7, 2010

A 65 year old man presented with hesitancy, frequency, dribbling, and sense of incomplete bladder emptying. Rectal examination revealed enlarged and nontender prostate. Urinalysis revealed no protein, glucose, WBCs, or RBCs. Serum prostate-specific antigen was 1.2 ng/mL (normally <4). Which of the following is the most appropriate treatment?

A- Alpha adrenergic antagonist
B- Sodium restriction
C- Antibiotics with activity against gram negative rods
D- Competitive inhibitor of prostate estrogen receptors
E- Loop diuretics

Seetal · Apr 7, 2010

khanar · Apr 7, 2010

Seetal said:
D

No it's not D, androgen receptor blockers are not used in BPH they are used only in prostatic cancer which is not the case here.
Therefore, you give only symptomatic treatment for this patient so the answer is A.

Also see this related question
http://www.usmle-forums.com/usmle-step-1-forum/1034-prostate-ca-rx.html

doctorF · Apr 7, 2010

A- alpha antagonist for sure

sohni · Apr 8, 2010

A

i think the answer is A

shakaib · Oct 25, 2010

Shakaib

A for 100% sure ...

Seetal · Oct 26, 2010

yeah A for sure. u see the difference. months back i answered A, but now with practice i know where there's no infection or when his BPH is not due to overactivity of DHT (low PSA), then u only need to ease his urination. alpha-blocker it is.

tabishnabil · Jun 14, 2011

answer A

Tricky , took me by suprise , i was thinking of the Dht blockers , but correctly mentioned its usefulness is well restricted for the treatment of Ca prostrate