[Betro Sadek]

The classical USMLE question describing a case of Chronic Granulomatous Disease and then asking you what other infection is the patient liable to get.

Of course you should be thinking of all of the catalase positive microorganisms.

Here's a mnemonic

SPACE

• Staphylococci (important not confuse it with streptococci)
• Pseudomonas aeroginosa
• Aspergillus fumigatus
• Candida
• Enterobacteriaceae (specially Klebsiella and Serratia both of which can cause pneumonia and UTI)

Worth to remember that none of the anaerobes are Catalase positive

Also some others are Catalase positive

• Nisseria (Gonorrhea & Meningitidis)
• Vibrio
• Nocardia
• Campylobacter & Helicobacter
• Gardnerella vaginalis
• Pseudomonas cepacia
• Mycobacterium Tebeculosis also produce a heat sensitive catalase ( active only in body temperature ) so it become catalase negative at 68.0 "F

 

[ahmednabil616]

Catalase positive organisms

Catalase positive organisms
SPACE:
Staphylococcus aureus
Pseudomonas
Aspergillus
Candida
Enterobacter

 

[menatallah Elgohary]

mnemonic for catalasve +ve organisms

Catalase +ve organisms- SPACE
Staph aureus
Pseudomonas
Aspergillus
Candida Enterobacter

 

[tyagee]

catalase positive
SPACE
Staph aureus
Pseudomonas
Aspergillus
Citrobacter
Enterobacter

CGD is SPACE +ve

 

[alphadoc]

CGD is deficiency of NADPH oxidase. As a result the body is not able to protect itself against infections such as those caused by catalase+ organisms (staphylococci, pseudomonas, aspergillus, candida, enterobacters = SPACE)

 

[herbitex]

dr.

hey guys thans for the mneomnics

 

[erickven]

Catalase +

Just saw this one in UW:

Burkholderia cepacia Happy-2

 

[drvsakethreddy]

one more

And also Serratia marcecens Happy-2

 

[drvsakethreddy]

OOPS

Oops i overlooked the Enterobacteriaceae thingy. Sorry guys.

 

[koolio852]

this is great. Thanks!

 

[Lostcause]

No HuBBLe SPACE CaMP

This has some missing information

New Mnemonic: No HuBBLe SPACE CaMP

Nocardia
o

Helicobacter pylori
u
Brucella
Burkholderia cepacia
Listeria/Legionella pneumophila
e

Staphylococci (aureus, epidermidis, saprophyticus)
Pseudomona
Aspergillus
Candida
Enterobacteriaceae

Corynebacterium
a
Mycobacterium tuberculosis
Pastereulla Multocida

with CAMP in itself a play for Campylobacter jejuni.

While Vibrio and Neisseria do produce catalase I dispute gardnerella vaginalis as being catalase negative, check sources.