[rasheed]

The Clotting PIANO
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• Thrombotic tendency as in (factor 5 leiden and antithrombin III deficiency)
• Cancer
• Pregnancy
• Injury to tissues (such as trauma and surgery) which releases tissue thromboplastin
• Advanced age
• Nephrotic syndrome
• Oral contraceptive pills

Hypercoagulable states are commonly tested in USMLE and it's one corner of the Virchow's triad together with endothelial injury and altered blood flow.