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Discussion Starter · #9 ·
Glad this thread is helpful; here's a couple more to add to the list:

CD 21: Receptor for the c3d component of complement and EBV .
CD 34: Early lymphohematopoeitic stem cell and progenator cell and function for cell- to- cell adhesion

Some extra info to add on what has already been said:

1. CD2--> Associated with T-antigen receptor/ "LFA2"
2. CD3--> Signal transduction complement of T-cells
3. CD4--> Found on all Helper T-lymphocytes
4. CD8--> Found on all Cytotoxic T-lymphocytes
5. CD10--> CALLA (Common Acute Lymphoblastic Leukemia Antigen) Functions as a metalloendopeptidase (Zn dep)/ Deactivated by chellators
6. CD16--> Fc receptor involved in binding to immune complexes and promoting antibody-dep cell mediated cytotoxicity. (NK cells)
7. CD19--> Is positive at the pro- B-cell stage/ MHC II antigens
8. CD20--> positive in a pro-B-cell
9. CD21--> As well as CD 19, form a receptor complex during B-cell activation.
10. CD56--> Marker for NK cells
11. TCR --> is positive once the T-cell has left the Bone marrow

Some things to watch out for:


12. Mature B-cell--> "naive" Will show both IgM and IgD
13. Mature T-cell--> will either be CD4 or CD8 not both
14. MHC I is stabilized by CD8
15. MHC II is stabilized by CD4 (Pro-cell stage)
16. immature T-cell is NEITHER CD4 nor CD8


I'll try to post a chart of what you see at each B-cell and T-cell stage as markers later on, and please add to the list if you have extra info.:)
 

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Glad this thread is helpful; here's a couple more to add to the list:

CD 21: Receptor for the c3d component of complement and EBV .
CD 34: Early lymphohematopoeitic stem cell and progenator cell and function for cell- to- cell adhesion

Some extra info to add on what has already been said:

1. CD2--> Associated with T-antigen receptor/ "LFA2"
2. CD3--> Signal transduction complement of T-cells
3. CD4--> Found on all Helper T-lymphocytes
4. CD8--> Found on all Cytotoxic T-lymphocytes
5. CD10--> CALLA (Common Acute Lymphoblastic Leukemia Antigen) Functions as a metalloendopeptidase (Zn dep)/ Deactivated by chellators
6. CD16--> Fc receptor involved in binding to immune complexes and promoting antibody-dep cell mediated cytotoxicity. (NK cells)
7. CD19--> Is positive at the pro- B-cell stage/ MHC II antigens
8. CD20--> positive in a pro-B-cell
9. CD21--> As well as CD 19, form a receptor complex during B-cell activation.
10. CD56--> Marker for NK cells
11. TCR --> is positive once the T-cell has left the Bone marrow

Some things to watch out for:


12. Mature B-cell--> "naive" Will show both IgM and IgD
13. Mature T-cell--> will either be CD4 or CD8 not both
14. MHC I is stabilized by CD8
15. MHC II is stabilized by CD4 (Pro-cell stage)
16. immature T-cell is NEITHER CD4 nor CD8


job well done boss!!!finish it please.
 

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I am confused about the differentiation of TH cells. The TH cells are CD4 cells ie they will attach only to the MHCII receptors. Then how do they differentiate into the two types of helper cells? how are the cytokines produced to stimulate the conversion of TH cell to TH1 or TH2?
 

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1. CD2????
2. CD3????
3. CD4- T helper cell
4. CD8- Cytotoxic T cell
5. CD10
6. CD16- NK cells
7. CD19
8. CD20 CD 19, 20,21- B cell
9. CD21
10. CD56- NK cells
11. TCR - Tcell
12. CD 1- langerhans cell
 
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