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It's important to memorize the risk of developing various infections and oppertunistic diseases at different CD4 counts landmarks in HIV infected patients.

CD4 count above 700 --->Normal
CD4 count 200-500 ---> Oral thrush, Kaposi sarcoma, TB, Zoster, and lymphoma
CD4 count 100-200 ---> PCP pneumonia, PML, Dementia, Histoplasmosis, and Coccidiomycosis
CD4 count 50-100 ---> Toxoplasmosis, Cryptococcosis, and Cryptosporodiosis
CD4 count less than 50 ---> CMV, Mycobacterium avium complex, CNS lymphoma
 

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CD4 counts are useful landmarks for initiation of prophylaxis

I think it's important to know when to start prophylaxis in immunocompromised patients;
The following CD4 counts are useful landmarks for initiation of prophylaxis:

  • < 200 cells/μL - PCP prophylaxis
  • < 100 cells/μL -Toxoplasmosis prophylaxis (if seropositive)
  • < 50 cells/μL - Mycobacterium avium-intracellulare infection prophylaxis
Please feel free to add:)
 

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a correxn

I think it's important to know when to start prophylaxis in immunocompromised patients;
The following CD4 counts are useful landmarks for initiation of prophylaxis:

  • < 200 cells/μL - PCP prophylaxis
  • < 100 cells/μL -Toxoplasmosis prophylaxis (if seropositive)
  • < 50 cells/μL - Mycobacterium avium-intracellulare infection prophylaxis
Please feel free to add:)
Prophylaxis for Toxo is given if u r sero negative
If u r sero positive, it implies that u r already been exposed 2 it & u r immune 2 it. so no need of prophylaxis
 

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sorry, I was wrong earlier

Prophylaxis for Toxo is given if u r sero negative
If u r sero positive, it implies that u r already been exposed 2 it & u r immune 2 it. so no need of prophylaxis
ag2011n was right

Toxo prophylaxis for those who are sero positive
Bcoz Toxo happens in AIDS pts due to reactivation of primary infection, when their CD 4 drops below 100 (this is something like tb)
 

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It's important to memorize the risk of developing various infections and oppertunistic diseases at different CD4 counts landmarks in HIV infected patients.

CD4 count above 700 --->Normal
CD4 count 200-500 ---> Oral thrush, Kaposi sarcoma, TB, Zoster, and lymphoma
CD4 count 100-200 ---> PCP pneumonia, PML, Dementia, Histoplasmosis, and Coccidiomycosis
CD4 count 50-100 ---> Toxoplasmosis, Cryptococcosis, and Cryptosporodiosis
CD4 count less than 50 ---> CMV, Mycobacterium avium complex, CNS lymphoma
CD4 count < 50........CMV Retinitis., JC virus/PML as well? please verify
 

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Prophylaxis for Toxo is given if u r sero negative
If u r sero positive, it implies that u r already been exposed 2 it & u r immune 2 it. so no need of prophylaxis
I think whether or not you're seronegative is moot, since you're going to be prophylaxing PJP with TMP/SMP at CD4 200, so you're kind of prophylaxing both PJP and Toxo at the same time. Any exceptions to this?
 
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