[khanar]

CD43 and CD43 am so confused about them
Can anybody help me differentiate these so that I can answer the related USMLE question.

Thanks

 

[khanar]

CD43 also called Sialophorin is associated with Wiskott-Aldrich syndrome. http://www.ncbi.nlm.nih.gov/pubmed/2223062

CD34 also called Sialomucin is a cell surface marker that is present mainly in hematopoeitic stem cells in the bone marrow and aids in cell migration and cell-cell adhesion.

 

[shafff111]

CD-34 marker on hematopoetic proginator cells

Found in AML.
Also distinguish Kaposi's sarcoma, dermatofibrosarcoma protuberans/DSFP (both CD34+) from dermatofibroma (CD34-)
:indifferent:

 

[shafff111]

CD-43,is a Pan T-Cell Marker

Also called leukosialin, sialophorin.
Has defective expression in T cells of males with Wiskott-Aldrich syndrome

 

[Hope2Pass]

Is this high yield? I haven't come across this before.

 

[shafff111]

CD markers r high yield

Is this high yield? I haven't come across this before.

yes they do ask questions about CD markers and these questions are almost always straight, to the point, short stem questions. in my step 1 exam i got three questions regarding CD markers of whch two i knew , and the third one i had never heard of :notsure: