[khanar]

A 4-month-old female is brought to her pediatrician by her mother who is concerned about some photographs she recently had developed. In the photographs, only the child’s right eye demonstrates a red reflex. Examination of the left eye confirms absence of a red reflex. Which of the following mechanisms is most likely involved?

A. Deletion in the long arm of chromosome 13
B. Deletion in the short arm of chromosome 5
C. Deletion of the short arm of chromosome 11
D. Nondisjunction of chromosome 18
E. Nondisjunction of chromosome 21

 

[marco]

Rb protein long arm of chromosome 13 retinoblastoma

 

[achistikbenny]

the child has retinoblastoma ,Rb gene suppressor mutation. so ans choice A is most likely correct

 

[Seetal]

I agree! definitely A (13q of the Rb gene)

 

[khanar]

Yes, it's Retinoblastoma

Yeah, You are all right

 

[shilpa narpat raj]

A 4-month-old female is brought to her pediatrician by her mother who is concerned about some photographs she recently had developed. In the photographs, only the child's right eye demonstrates a red reflex. Examination of the left eye confirms absence of a red reflex. Which of the following mechanisms is most likely involved?

A. Deletion in the long arm of chromosome 13
B. Deletion in the short arm of chromosome 5
C. Deletion of the short arm of chromosome 11
D. Nondisjunction of chromosome 18
E. Nondisjunction of chromosome 21

ans is A child has retinoblastoma which is due to Rb1 gene mutation on the chromosome 13

 

[apx85]

Retinoblastoma = Deletion of long arm of Chromosome 13

I choose A