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cholera toxin mechanism of action

6421 Views 7 Replies 5 Participants Last post by  Medstu19
does cholera toxin causes increase in no of chloride secretory channels in epithelium ?
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As patelmd and aktorque said... cAMP activates PKA which phosphorylates the CFTR channel. The pattern is the familiar; the target in this case is the CFTR chloride channel, just like with heat-labile enterotoxin.
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