USMLE Forums banner

cholera toxin mechanism of action

6421 Views 7 Replies 5 Participants Last post by  Medstu19
does cholera toxin causes increase in no of chloride secretory channels in epithelium ?
1 - 1 of 8 Posts
As patelmd and aktorque said... cAMP activates PKA which phosphorylates the CFTR channel. The pattern is the familiar; the target in this case is the CFTR chloride channel, just like with heat-labile enterotoxin.
  • Like
Reactions: 1
1 - 1 of 8 Posts
This is an older thread, you may not receive a response, and could be reviving an old thread. Please consider creating a new thread.