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A 30-year-old female presents to her primary care physician with complaints of frequency, urgency, and dysuria over the last twelve hours. Urinalysis reveals many leukocytes. She is treated with a three-day course of oral ciprofloxacin. What is the primary target of the antimicrobial action of ciprofloxacin?

A. Binding of the 30S subunit
B. Binding of the 50S subunit
C. Competitive inhibition of dihydrofolate reductase
D. Inhibition of DNA-dependent RNA polymerase
E. Inhibition of DNA gyrase
 
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