[lee-usmle]

38 YO Man presented with six months diarrhea and weight loss. PE showed melanoderma and knee arthritis. Stool fat content is increased. Biopsy of the small intestine showed the following micrograph;

Picture from Wikimedia Commons

What is the diagnosis?
A- Pancreatic insufficiency
B- Celiac Sprue
C- Diverticulosis
D- CA Colon
E- Crohn disease
F- Whipple disease
G- Intestinal lymphangiectasia

 

[smile135]

F Whipple disease ??

 

[ahassan]

I also think it is Whipple's disease

 

[lee-usmle]

Correct answer

You guys got right. This is Whipple Disease and the histopathology slide is showing the rod shaped microorganisms within faomy macrophages in the lamina properia.