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Discussion starter · #21 ·
@nick...I'll be starting 3rd video in half hr after dinner, just came back from gym, so wow...he didnt cover lysosomal dz well huh. Oh well, some of the topics, he does run through.
 
Discussion starter · #22 ·
because when u actually use ur hand write the answers to questions.. U must reach the point where u say to urself... "looks like somebody hasnt been studying with his heart, thinks he's studying for a medical school exam where i can just memorize the last three letters of that drugs name and then i'll be able to answer the MCQ on the test''.. But not for step1 baby
Only hard work will pay off, my advice is study with full conscience and no cheating, after finishing three videos study the material like if the test was tomorrow... Even if takes 40 days, not just 21, its more important than solving questions.. Coz u only have to do this once, do it good,,,, and after that, a full thorough read of FA can be done in less than a week if the DIT course is given its right dedication and detirmination
What do you mean by " only hard work will pay off, study with full conscience, no cheating , i can just memorize the last three letters of that drugs name and then i'll be able to answer the MCQ on the test''.. But not for step1 baby " .
How do know all these people are not working hard, not studying with full conscience, and are cheating ( btw cheating who?). Some of us are studying for 10-14 hours /day, and revising everything at the end of 3 lectures- I don't know if you heard dr.jenkins right, he says to solve qs along with his course, thats why all these people are applying their knowledge and raising their scores, nothing wrong with it..... then why are you saying..."Even if takes 40 days, not just 21, its more important than solving questions.. "

BTW, didn't you couple of days ago post this "

im starting day 3, video #2 now
tomorrow [friday and saturday] is my weekend, im tearing that thing apart, hope to do days 3 [4,5,6] during the weekend, and finish day#3 today
You are advising us to do it in 40 days yet you want to do 3 days lectures in 2 days.

We all are trying to do our best in our own way, so please be kind not to negatively put others effots down. Thank you.
 
Discussion starter · #23 ·
done with day 10 vids. He brushed through many parts of genetics, had to read thru kaplan LN (which I read long time ago) to understand concepts.
He explained gel electrophoresis well, & yeah lysosomal storage dz- he didn't even read a word from FA...directly went to quiz, but he said it is not HY ( which I didnt expect)...saves me a lot of trouble...I remember spending a lot of time studying it...practising the enzymes & products pathway, now I'm going to brush thru the main differentiating points. Exhausted..I have been hanging with these books for 14 hrs now....time to call it a night. GN
 
Discussion starter · #25 ·
Anti-Androgens:
Finasteride- rx of BPH, male pattern balding
Flutamide- only in rx of prostrate cancer.
Ketoconazole & Spironolactone-
- used in rx of PCOS to prevent hirsutism.
- They have SEs of Amenorrhea & gynaecomastia---why? is it b'coz of dec testosterone---> inc estrogen?
 
Ketoconazole & Spironolactone-
- used in rx of PCOS to prevent hirsutism.
- They have SEs of Amenorrhea & gynaecomastia---why? is it b'coz of dec testosterone---> inc estrogen?
they block androgens (test and estrogen) at their receptors so they cant perform their actions
estrogen cant perform its action on the endometrium, so amenorrhea
testosterone not performing its action in men = gyno
 
Discussion starter · #27 ·
There went my 1 hour....my mom called & I ended up spending 1 hr on phone.I still have to finish 1st lecture of the day..ugh.
 
Discussion starter · #28 · (Edited)
@nick..I didn't see your explanation before, thanks....makes sense. may be I missed it, where did it say they act on receptors, I dint know that, only knew that they inhibit steroid synthesis & binding.
How is your prep coming along.
 
@nick..I didn't see your explanation before, thanks....makes sense. may be I missed it, where did it say they act on receptors, I dint know that, only knew that they inhibit steroid synthesis & binding.
How is your prep coming along.
prep is ok
starting day11vid1 now
scored 60% in UW today, not great but still in the 60s, which is where i want to consistently be right now.
 
Discussion starter · #31 ·
@pathophysio1..... my plan is to take by june 5th...hopefully will be ready & not postpone it.

@nick....60s consistently is very good...in next few weeks, maybe u'll jump to 70s....GL. I am planning to subscribe(2nd time) to UW as soon as I finish DIT ( 4-5 more days) and will start doing UW + nbmes + FA revision.

On to 2nd vid of the day.
 
Discussion starter · #37 ·
my nbme scores would beg to differ
DITs my last hope to get up in the 210 range
im just aiming for 220.
I`m sure you`ll get more than 220 w/ those uw scores & FA 3 times done + DIT and you have 6 more weeks.

How did you study cellular biochem....really bogging me down. Just studied those CDKs & cyclins from DIT notes...how imp are they? It's all pure memorization.
 
I`m sure you`ll get more than 220 w/ those uw scores & FA 3 times done + DIT and you have 6 more weeks.

How did you study cellular biochem....really bogging me down. Just studied those CDKs & cyclins from DIT notes...how imp are they? It's all pure memorization.
i think that CDK stuff he talked about today is overkill
thats too indepth
that wont be on step1

no other source goes into that much detail of describing every type of CDK.

just know what a CDK is
and know all the apoptosis pathways and cell cycle stuff and its enough

p53, bax, bcl-2, cyclin D, etc is what u need to know.
 
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