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- They all block Na reabsorption along the tubule
- They all cause hypokalemia EXCEPT K sparing diuretics
- Thiazides cause hypertriglyceridemia EXCEPT Indapamide
- K sparing diuretics are antiandogenic EXCEPT Eplerenone
- Loop diuretics cause sulfa allergy EXCEPT Ethacrynic acid
- Hyperglycemia mostly caused by Thiazides
- Only Thiazides cause hypercalcemia, all others cause hypocalcemia
- Acidosis is seen with carbonic anhydrase inhibitors and K sparing diuretics
- Alkalosis is seen in loop and Thiazides diuretics
- Hyperchloremia is seen only in carbonic anhydrase inhibitors
- Caffeine works on vasodilating the glomerular vessels unlike all other diuretics which work on blocking Na reabsorption
- Carbonic anhydrase inhibitors paradoxically cause renal stones because they result in basic urine (bicarbonateuria)
