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PPI is the answer

As far as I know that PPI are associated with SBP (spontaneous bacterial peritonitis) this in turn may precipitate hepatic encephalopathy.
 
R

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Colchine used in gout ..
Its true PPI may worsen SBP .... Thanks for that coz i forgot that ..
But its not PPI ....
So you mean Colchicine not colchine :)
If PPI is not the answer then what is it? Please tell me :(
 

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Colchine used in gout ..
Its true PPI may worsen SBP .... Thanks for that coz i forgot that ..
But its not PPI ....
How about frusemide ?
IS that the drug which can coz changes in K level in bloob ?
I think changes in K level in blood could precipitate encephalopathy.
 
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How about frusemide ?
IS that the drug which can coz changes in K level in bloob ?
I think changes in K level in blood could precipitate encephalopathy.
What is the mechanism by which hypokalemia causes hepatic encephalopathy!?
 

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More ammonia in alkalosis

What is the mechanism by which hypokalemia causes hepatic encephalopathy!?
The hypokalemia and metabolic alkalosis seen with any diuretic therapy (except K+ sparing) will favor the conversion of NH4+ to NH3 thereby contributing to more ammonia formation and worsening or precipitating the encephalopathy.
 
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woow

The hypokalemia and metabolic alkalosis seen with any diuretic therapy (except K+ sparing) will favor the conversion of NH4+ to NH3 thereby contributing to more ammonia formation and worsening or precipitating the encephalopathy.
Woow, thank you for the explanation
 

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Discussion Starter #12
Dehydration , infection , electrolyte abnormality ( decre.K+ & increa HCO3-), sedative , GI bleeding = all of this condition worsen encephalopathy ...
In cirrhosis diuretics is used for edema and ascitis , so if it used excessively for edema ,it may cause dehydration and elec abnormality which worsen encephalopathy .......
 
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