[aniraiqbal93]

I know this is a commonly tested upon topic and here it is simplified, and the way I remember it :-

We know Sulfa and Nitro drugs are oxidizing agents. Hence they cause 2 important effects :-
1. They oxidize Fe2+ to Fe3+ and so cause Methemoglobinemia
2. They form peroxide which causes hemolysis in G6PD deficient patients

These drugs are -

Sulfa drugs like
1. Dapsone
2. Primaquine
3. Trimethoprim - sulfamethoxazole
4. Sulfonamides

Nitro drugs like -
1. Nitroglycerine
2. Nitroprusside
3. Nitrofurantoin
4. Nalidixic acid

Hope this was helpful. Please add to the list if any drug left out.

 

[medystudent]

very helpful thank you