[preeti617]

cardiac murmurs

Does Increasing afterload intensify murmer of MVP or decrease it like HOCM ??? What is the mechanism of so in MVP ?

Increasing afterload will intensify the murmur of MVP as there is an obstruction to LV emptying so there is more regurgitation during that time into the LA as that is a path of less resistance .
In HOCM the IVS is hypertrophied and obstructs the outlet by the anterior mitral valve leaflet and hence obstructs LV outlet. This obstruction will be enhanced if LV volume is decreased and murmur will increase.Hence in HOCM the preload will determine the intensity of murmur.