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Discussion Starter · #1 ·
The incidence of PKU in a population is 1 in 6,400 individuals. A woman from this population marries a phenotypically normal man who had an uncle with PKU. What is the risk that this couple will have a child with PKU?

1) 1/480
2) 1/6,400
3) 1/80
4) 1/40
5) 1/3,200

Woman's risk: 1/40
Man's risk: ???? (I think ?)
Mendelian: (¼)


Can someone please explain how to calculate the man's risk?
 
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