[donofitaly]

Do GH and Prolactin use Tyrosine Kinase pathway for their action? In FA2010 Errata it was pointed as a mistake but most other sources say it is the mode of action. Please help.

 

[ashishkabir]

Yeah - I think it uses a JAK-STAT pathway - here:

http://www.ncbi.nlm.nih.gov/pubmed/8815791

What is a JAK-STAT pathway you ask? Here you go

http://en.wikipedia.org/wiki/JAK-STAT_signaling_pathway

I'm not sure how much of this detail is essential - but here it is anyway...

 

[khanar]

Found a related great talk

Guys, have a look at this great thread
http://www.usmle-forums.com/usmle-step-1-forum/1496-pathways-receptor-signaling.html