[khanar]

On a pre-employment check up the patient was found having the following profile.

• HBsAg Negative
• Anti-HBs Positive
• Anti-HAV (IgG) Positive
• Anti-HAV (IgM) Negative
• Anti-HBc (IgG) Positive
• Anti-HBc (IgM) Negative
• Anti-HCV Negative

Which of the following is true?
A- Acute Hepatitis A infection
B- Window period
C- Vaccinated against Heptitis B
D- Recent Hepatitis B infection
E- Chronic Hepatitis B infection
F- Old Hepatitis B infection
G- Inactive Hepatitis B carrier

 

[wahaha007]

I'll simply chose C.

 

[Doc-Yuvi]

Answer is F. Anti-HBsAg and Anti-HBcAg (IgG) is present as well.

(if it was only Anti-HBsAg, then it is immunization)

 

[Mohabravo]

Exactly ... I think " F " is correct .... If its immunization only, you should have only Anti HBs IgG only.
While during the " window period " or choice "C", you will have only Anti HBc IgM +ve.
In Old infection, there will be +ve Anti HBs IgG and +ve Anti HBc IgG .....

 

[umer_dow]

The answer is F..

 

[Mohabravo]

Any one know what is seen in Hepatitis B carriers ? ... What are the +ve Ab ?

 

[umer_dow]

hepatitis B carrier: Anti HBs (IgG)
Anti HBc (IgG)

 

[khanar]

The correct answer is F

OK guys you got it right.

Old Hepatitis B = The infection has resolved, so HBsAg disappears and Anti-HBs antibodies and Anti-HBc antibodies will be there as in the case above.

Inactive carrier = Is exactly like the old resolved infection but with the difference of higher DNA viral loads implying viral continued reproduction. This is not mentioned in the case above.

Chronic Hepatitis B = The infection persisted, so HBsAg will continue to be there which is not the case above.

Immunized = Only the Anti-HBs antibodies are there and you won't see Anti-HBc as in the case above.

Window period = You won't see the Anti-HBs antibodies as in the case above. The window period is the time between disappearance of the HBsAg and appearance of Anti-HBs antibodies.

 

[Medstu19]

Sorry guys, but i think i'm missing something, why is there a positive HAV IgG, previous vaccination?. Thanks

 

[DocSikorski]

Truly F....