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:notsure:

Hi guys,

Considering the fact that most grads might be out of tune with calculations over the years. It will be good to see how high yield the calculation questions really are.

Those who have taken step 1 should please list the high yield topics from which calculations might be required.
thanks.
 

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Here's the list of equations needed

You will be asked to calculate the following:

Physiology equations such as:
The cardiac output and mean blood pressure and vascular resistance equation.
Filtration fraction equation
Body weight and the ICF and ECF ratios
ventilation equations

Biochemistry equations such as:
Purines and pyrimidine ratio
PH, Pka calculations

Pharmacology equations:
All the pharmacokinetics equations are needed like those about the clearance and volume of distribution

And of course the genetics and biostatistics are all high yield such as the sensitivity, Hardy Weineberg, odds ratio, ...etc

Hope that helps :eek:
 

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cardiac output= s.v x HR

MAP= COx PVR

CO= o2 consumption/arterial - venous o2 content times 100

FF=GFR/RPF

TLC (total lung capacity)= vital capacity + residual volume

or its the sum of inspiratory and expiratory capacity

IC = IRV +TV

EC= FRC + RV

volume of distribution= dose /concentration

Clearence cl= Vd x Ke

Ke= 0.7/t 1/2

cl=0.7 x Vd / t1/2

or t1/2 = 0.7 x vd / cl

maintanence dose = C ss x Cl/F

loading dose= Css X Vd/F

total body water is 60% of the total body weight

2/3 rd of the total body water is ICF and 1/3 rd is ECF

of that ECF 1/3 rd----- 3/4th is interstium and 1/4 th is plasma

p2+2pq+p2= 1 , p+q=1 hardy weinberg equation
 

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Check the First aid for step 1 book..
There are 2 pages at the end containing MUST KNOW equations..
Also make sure to read the Biostatistics section of first aid as the equations there are really important, also do practice on the equations using UW! I got really tough biostat equations in the step 1, but thanks to UW that made them easier for me during exam time.
Also NBMEs include type of questions really similar to real exam.
Good luck
 

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cardiac output= s.v x HR

MAP= COx PVR

CO= o2 consumption/arterial - venous o2 content times 100

FF=GFR/RPF

TLC (total lung capacity)= vital capacity + residual volume

or its the sum of inspiratory and expiratory capacity

IC = IRV +TV

EC= FRC + RV

volume of distribution= dose /concentration

Clearence cl= Vd x Ke

Ke= 0.7/t 1/2

cl=0.7 x Vd / t1/2

or t1/2 = 0.7 x vd / cl

maintanence dose = C ss x Cl/F

loading dose= Css X Vd/F

total body water is 60% of the total body weight

2/3 rd of the total body water is ICF and 1/3 rd is ECF

of that ECF 1/3 rd----- 3/4th is interstium and 1/4 th is plasma

p2+2pq+p2= 1 , p+q=1 hardy weinberg equation
Thanks a lot, OMG I hate calculations ... SO HARD! :mad: :eek:
 
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