[rasheed]

45 year old male presented with substernal chest pain.
Histological examination revealed this

Image from wikimedia commons

This is an example of;
a- Carcinoma in situ
b- Metaplasia
c- Dysplasia
d- Anaplasia
e- Hyperplasia

 

[shininggirl]

metaplasia

 

[ashishkabir]

Is this Barret's Esopahagus? A little more in the question stem would have helped

 

[rasheed]

Correct

metaplasia

Correct

 

[rasheed]

Correct

Is this Barret's Esopahagus? A little more in the question stem would have helped

You guessed it right without the need for other clues

 

[rasheed]

Answer: Barrett's Esophagus - Metaplasia

The slide shows typical changes of Barrett's esophagus where the stratified squamous epithelium (to the right) has been replaced by gastric columnar epithelium (to the left) which is also characterized by goblet cells in the surface epithelium and formations of glandular structures.

Gastroesophageal reflux disease (patient with heartburn and substernal pain) is the cause and it's considered as a precancerous condition predisposing to esophageal adenocarcinoma (not squamous) which is the most common type of esophageal cancer in USA.

 

[indian]

Can I ask where did you get the question from, which bank?

 

[rasheed]

Can I ask where did you get the question from, which bank?

None, this is my work only

 

[syedaanaqvi]

this pic was taken from robbins

 

[rasheed]

this pic was taken from robbins

I've taken the picture from this wikipedia page
http://en.wikipedia.org/wiki/File:Barretts_alcian_blue.jpg
the image is in the public domain
I don't know whether if originally it was taken from Robbin's

 

[shininggirl]

I said it metaplasia, because there was substernal pain, which indicates stomach or lower esophagus problem commonly, and slide showedd columnal cells with glands. normally esophagus has squamous cells and stomach has cuboidals cell, so in this slide there are columnal(intestinals) cells which mean it is metaplasia.

 

[syedaanaqvi]

I said it metaplasia, because there was substernal pain, which indicates stomach or lower esophagus problem commonly, and slide showedd columnal cells with glands. normally esophagus has squamous cells and stomach has cuboidals cell, so in this slide there are columnal(intestinals) cells which mean it is metaplasia.

nice way to answer!