USMLE Forums banner

1 - 12 of 12 Posts

·
Registered
Joined
·
741 Posts
Discussion Starter #6
Answer: Barrett's Esophagus - Metaplasia

The slide shows typical changes of Barrett's esophagus where the stratified squamous epithelium (to the right) has been replaced by gastric columnar epithelium (to the left) which is also characterized by goblet cells in the surface epithelium and formations of glandular structures.

Gastroesophageal reflux disease (patient with heartburn and substernal pain) is the cause and it's considered as a precancerous condition predisposing to esophageal adenocarcinoma (not squamous) which is the most common type of esophageal cancer in USA.
 

·
Registered
Joined
·
47 Posts
I said it metaplasia, because there was substernal pain, which indicates stomach or lower esophagus problem commonly, and slide showedd columnal cells with glands. normally esophagus has squamous cells and stomach has cuboidals cell, so in this slide there are columnal(intestinals) cells which mean it is metaplasia.
 

·
Registered
Joined
·
29 Posts
I said it metaplasia, because there was substernal pain, which indicates stomach or lower esophagus problem commonly, and slide showedd columnal cells with glands. normally esophagus has squamous cells and stomach has cuboidals cell, so in this slide there are columnal(intestinals) cells which mean it is metaplasia.
nice way to answer!
 
1 - 12 of 12 Posts
Top