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HLA Associations

34454 Views 13 Replies 12 Participants Last post by  ddeneve
Ms SLE DeMands Ribose Additions to Her Nutrition

Multiple Sclerosis DR2
SLE DR2/DR3
Type I Diabetes Mellitus DR3/DR4
Rheumatoid Arthritis DR4
Hashimoto's thyroiditis DR5
Nephrosis, steroid responsive DR7

(note the gradual increments in the DR numbers)

You are left with B27 and everybody should know that it's associated with ankylosing spondylitis, Reiters, IBD, Psoriatic arthritis

And DQ, where it increase the risk for celiac disease and DM (that's the association between the two)

And B8, also seen in celiacs and Grave's disease

And A3, seen in hemachromatosis
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Do they really ask about these numbers?
Oh yes, they sure do

You definitely going to see it in your step 1 at least the DM, the SLE, or the RA associations
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G
Thank you very much, this is really helpful
HLA and Relative Risk

Which HLA association has maximum relative risk for a disease? Answer will be posted tomorrow. Take a shot!
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Hla b27

Which HLA association has maximum relative risk for a disease? Answer will be posted tomorrow. Take a shot!
I'd say HLA B27 and the ankylosing spondylitis
Am I right!
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I like mnemonics that are found in the words they represent..

I think this would make more sense if I could draw it. You have to draw the numbers so they looks similar to the letters that they represent.
Just associate the backwards 3 with E and 4 or 8 with A and 5 with S and 7 with Y and backward with F or T and forwards 2 with S. It sounds difficult but it's really easy, try drawing them out. :)

A3 = Hemochromatosis = A3mochromatosis

B27 = PAIR mnemonic in FA

DR2 = Multiple Sclerosis = Mul2iple Sclerosis,
Hay Fever = Hay 2(backwards)ever
Goodpasture's Syndrome = Goodpas2(backwards)ure's
SLE = 2LE

Grave's Ds = Gr8ve's Disease

Diabetes Type 1 = Dia4b3tes

RA = Rheum4toid Arthritis

Hashimoto's Thyroiditis = Ha5himoto's Thyroiditis

Pernicious Anemia = Pentad means 5

Steroid Responsive Nephrotic Syndrome = Nephrotic S7ndrome
See less See more
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Poem for HLA

Well I made this Poem for HLA and it has served me well so far.. didnt seem to forget.. so hopefully it will be of use to all of you.

DR2-Dr3 my kidney got some SLE
When its just DR2 its either MS or goodpast(2)ure

Dr3-DR4 Insulin i want you more (IDDM)
When its just DR4, my knuckles really get so sore (RA)

You took you ate (HLA2-Q8) Sil tastes so great (coeliac)
Be you 8 or 27 (B8,B27), your neck and spine will keep you even (Thyroiditis, AS)
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B8
Think "SEE 8's" See = Celiac Disease
A sideways 8 looks like a Thyroid ∞ = Grave's Disease

DR2
Called Dr. 2 say "Hay, MS. SLE's Good"
DR2
Hay Fever
MS
SLE
Goodpasture's
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its confusing

I think this would make more sense if I could draw it. You have to draw the numbers so they looks similar to the letters that they represent.
Just associate the backwards 3 with E and 4 or 8 with A and 5 with S and 7 with Y and backward with F or T and forwards 2 with S. It sounds difficult but it's really easy, try drawing them out. :)

A3 = Hemochromatosis = A3mochromatosis

B27 = PAIR mnemonic in FA

DR2 = Multiple Sclerosis = Mul2iple Sclerosis,
Hay Fever = Hay 2(backwards)ever
Goodpasture's Syndrome = Goodpas2(backwards)ure's
SLE = 2LE

Grave's Ds = Gr8ve's Disease

Diabetes Type 1 = Dia4b3tes

RA = Rheum4toid Arthritis

Hashimoto's Thyroiditis = Ha5himoto's Thyroiditis

Pernicious Anemia = Pentad means 5

Steroid Responsive Nephrotic Syndrome = Nephrotic S7ndrome
well that really dazzled me :rolleyes:
HLA B8 Mnemonic

Here's a mnemonic for HLA-B8:

Mercedes AMGG has a B8 (V8) Engine:

Addison's
Myasthenia Gravis
Grave's
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Haemochromatosis

hA3mo-chromosome6

HLA-A3
HFE gene on chromosome 6
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