Renal insufficiency, as a result of immune complex-mediated glomerulonephritis, occurs in less than 15% of patients with endocarditis and may cause hematuria but rarely azotemia.
In neonates, endocarditis commonly produces septic embolic phenomena, such as osteomyelitis, meningitis, and pneumonia. Neonates with endocarditis may also have feeding problems, respiratory distress, tachycardia, or neurologic symptoms.
Vascular phenomena (arterial emboli, septic pulmonary infarcts, intracranial hemorrhage, conjunctival hemorrhage, Janeway lesions [painless, hemorrhagic lesions on palms and soles])]
Immunologic phenomena (glomerulonephritis, Osler nodes, Roth spots, positive result for rheumatoid factor)