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Discussion Starter · #1 ·
At autopsy, a patient who died with acute anuria and uremia is found to have ischemic necrosis of the cortex of both kidneys with relative sparing of the medulla. These pathological findings are most likely related to which of the following underlying conditions?

A) Disseminated intravascular coagulation
B) Multiple myeloma
C) Polycystic kidney disease
D) Pyelonephritis
E) Sickle-cell anemia
 

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Multiple myeloma - Bence Jones proteins
PKD - cysts compress everything
Pyelonephritis - renal pelvis and tubules, after this cortex
Sickle-cell anemia - can cause acute papillary necrosis

So left Choice A
 
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