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Discussion Starter · #1 ·
At autopsy, a patient who died with acute anuria and uremia is found to have ischemic necrosis of the cortex of both kidneys with relative sparing of the medulla. These pathological findings are most likely related to which of the following underlying conditions?

A) Disseminated intravascular coagulation
B) Multiple myeloma
C) Polycystic kidney disease
D) Pyelonephritis
E) Sickle-cell anemia
 

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A. Dic

DIC (post obstetrical emergency or from any other cause) may result in diffuse cortical necrosis. I'd say DIC-
 

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Multiple myeloma - Bence Jones proteins
PKD - cysts compress everything
Pyelonephritis - renal pelvis and tubules, after this cortex
Sickle-cell anemia - can cause acute papillary necrosis

So left Choice A
 

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Discussion Starter · #4 ·
yup its A

in option given only DIC can result in cortical ischemic necrosis with sparing of medulla...
 
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