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Whenever you see a female patient with any of the following clinical features then you have to suspect Antiphospholipid syndrome and it's always asked about in CK exam.
The features are:

  • DVT (leg swelling)
  • Pulmonary embolism (dyspnea, chest pain, cyanosis, sudden death, ...etc)
  • H/O repeated abortions
  • Increased PTT
  • Thrombocytopenia
  • Livedo reticularis
Of course there are several other manifestations of APS but these are the main ones that are commonly mentioned.
 

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Whenever you see a female patient with any of the following clinical features then you have to suspect Antiphospholipid syndrome and it's always asked about in CK exam.
The features are:

  • DVT (leg swelling)
  • Pulmonary embolism (dyspnea, chest pain, cyanosis, sudden death, ...etc)
  • H/O repeated abortions
  • Increased PTT
  • Thrombocytopenia
  • Livedo reticularis
Of course there are several other manifestations of APS but these are the main ones that are commonly mentioned.
Here I want to add one more thing,whenever PTT is raised that usually lead to bleeding disorders but its a paradox here a thromboembolic disease with a raised PTT.The reason is we use phospholipid Abs in the lab while measuring PTT.
 
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