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Abbreviations: AgRP, Agouti-related peptide; BDNF, brain-derived neurotrophic factor; CART, cocaine and amphetamine related transcript; MC3R, melanocortin 3 receptor; MC4R, melanocortin 4 receptor; NPY, neuropeptide Y; POMC, pro-opiomelanocortin gene; TrkB, tyrosine kinase receptor B; Y1R, neuropeptide Y receptor Y1.

Leptin-induced signaling in the Arcuate nucleus of the hypothalamus. Mutations in ligands and receptors of the leptin-melanocortin pathway that lead to obesity.
 
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