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Discussion Starter · #1 ·
Below is the list of important drugs that have active metabolites;


1) Acetohexamide (can cause renal dysfunction)

2) Atracurium = Laudanosine(can cause seizures)

3) Acetaminophen = N-acetyl benzoquinonamine (hepatic necrosis & failure)

4) Ethanol = Acetaldehyde (folate inactivation & thimine ,disulfiram like reaction)

5) Morphine = Morphine 6 glucoronide(renal toxic)

6) Meperidine = Nor meperidine(Serotonin synd)

7) Glyburide (renal dysfunction)

8) Imepinem (nephrotoxic metabolite)

9) Sulfonamide (crystalluria)


(you are welcome to add more to the list:) )
 
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