USMLE Forums banner
1 - 4 of 4 Posts

26 Posts
Discussion Starter · #1 ·
Y-linked transmission:
The Y chromosome has a trivially simple inheritance pattern because women are XX and men are XY. Only men have a Y chromosome and so the Y is only passed from father to son.

Male sex determination:
The main Y gene is called the SRY gene, which is the master gene that specifies maleness and male features. It is the single gene that sets off the initial cascade of hormone changes that make a person male.

List of Y-Linked Diseases:
The Y chromosome is relatively small and contains very few genes, there are relatively few Y-linked disorders.

  • Male Infertility
  • Excessive hair on the ear pinna (Hypertrichosis pinnae)
  • Retinitis pigmentosa
  • Color blindness
  • XYY syndrome
XYY syndrome is another proof that the Y chromosome doesn't have really many genes that determine human structure. These patient have no specific physical features except perhaps for increased height. But they usually have learning disabilities, aggressive behavior, and severe acne.
1 - 4 of 4 Posts
This is an older thread, you may not receive a response, and could be reviving an old thread. Please consider creating a new thread.