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Discussion Starter · #1 ·
Hello dear colleagues,

While studying from Kaplan and Reviewing from FA, I encountered some information that is rather confusing to me.

In Kaplan (Pharmacology), it is stated that the mechanism of action of local anesthetics is to block the inactivated Na+ channels (pg. 147), while in FA it is stated that the mechanism of action is by binding to activated Na+ channels (pg. 411).

If anyone has an input it would be very much appreciated.

Thanks
 
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