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Microscopic Hematuria in African American Woman?

3042 Views 4 Replies 3 Participants Last post by  pakbrain, 
M
A young African American woman has normal physical exam except lab study reveals microscopic hematuria, BUN and creat normal. what is the first step in work up?

:rolleyes: hint .... oxygen tension in renal medulla
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M
the answer is along the same thought process.
but the question is - what is the first step in workup

in renal papillary necrosis --> gross hematuria and proteinuria.
renal papillary necrosis may be associated with Diabetes mellitus, Acute pyelonephritis, Chronic phenacetin use [acetaminophen is phenacetin derivative], and Sickle cell anemia
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M
first step in workup is - Sickle cell screen
WHY - This patent probably has sickle cell trait. Oxygen tension in renal medulla is low enough to induce sickling in peri-tubular capillaries leading to microinfarctions
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