[dakshmalhotra]

why there is Na retention in c/o hyperinsulinemia ??

 

[Haisook]

I'd like to know as well.
I just know that hyponatremia can be caused by hyperglycemia, hyperlipidemia, or hyperproteinemia.

 

[dakshmalhotra]

well i read this stuff in goljan which state this statement...i thought opposite as insulin tend to shift k+ into the cell so Na will come out... i am still searching the answer.

 

[md5rr]

?pseudohypernatraemia

Hyperglycaemia causes pseudohyponatraemia, via osmotic dilution of plasma.
Maybe in the same way, hyperinsulinaemia leads to a drop in plasma [glucose]. This would in turn reduce the plasma osmolality (normally a function of [Na], [urea] and [glucose]).
By rearranging the equation, a reduced glucose, and a reduced osmolality would lead to a pseudohypernatraemia.

Just a thought