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· Ex-USMLE Forums Staff
752 Posts
Discussion Starter · #1 ·
Nikolsky's sign is a buzzword that should lead us to think of a number of skin conditions. However, frequently, the USMLE question maker will not often tell you the name out-rightly instead they usually describe it. Common descriptions include one of the two followings:
Rubbing the skin leads to sloughing of skin.
Lateral traction of the surrounding skin leads to sloughing (desquamation).

Now what causes that we should be thinking of?

  • Staphylococcal Scalded Skin Syndrome
  • Toxic Epidermal Necrolysis
  • Bullous impetigo
  • Pemphigus vulgaris (but not bullous pemphigoid) Read more
  • Epidermolysis bullosa
  • Second degree and Third degree burns
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