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A pharmaceutical company has developed a drug that prevents egress of Mg+2 from N-methyl D aspartame (NMDA) receptor. What is most likely effects of this drug in a patient with acute stroke?

A) Decreased risk of seizures because of hypomagnesima
B) Facilitation of Ca entry into neuron and enhancement of excitation mediated cell death
C) Hyperpolarization of membrane and conduction block
D) Prevention of Ca+2 entry into neuron and reduction of excitation mediated cell death
E) Rapid depolarization of membrane with lowering of seizure threshold
 
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