[DrSeddik]

I don't like NMDA receptors, I get seriously irritated when I see them in a question, so if anybody knows any high yield information other than these about them, please share.

- Ketotifen and PCP are NMDA antagonists, both were essentially anaesthetic agents, PCP is now only abused with Marijwana.
- Neurotransmitter is Glutamate, with the help of glycin
- They are CNS stimulants
- Blockade prevents tolerance to opioids.

 

[DrSeddik]

This is realy helpful. But what do you mean by (NMDA receptor open channel blockers), does it mean they only act on stimulated NMDA receptors ? Also in memantine (use dependant blocker)?

 

[DrSeddik]

Plz I want to know relation beteen NMDA receptors and Glycine

It's been mentioned, it's a cofactor for the stimulator glutamate