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some other important points I came across:

1. The NMDA receptor is important clinically bcz its hyperactivity causes excessive influx of Ca ions, this is known as glutamate toxicity, especially in the caudate nucleus leading to cell death and is implicated in Huntington disease.

2. this receptor is involved in the learning process through longterm potentiation in the hippocampus.
some where is also mention that valproic acid blocks the NMDA receptors and thereby affecting the potassium current
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